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(PDF) Human mitochondrial DNA: analysis of 7S DNA from the …
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WebAug 1, 2010 · In an in vitro assay where the release of 7S DNA from mtDNA was induced either by recombinant TFAM or 1-methyl-4-phenylpyridinium (MPP +), pre-treatment of isolated mtDNA with recombinant mtSSB prevented the 7S DNA release .This prompted us to analyse whether mtSSB is involved in the regulation of 7S DNA in living cells. Total … WebJan 2, 2024 · Coding and non-coding DNA Mitochondrial genes The only region lacking any known coding DNA is the displacement (D) loop region. D loop is the region in which a … WebJul 6, 2024 · However, quantification of mtDNA deletions, as well as of mtDNA copy number or DNA 7S performed on muscle biopsy, failed to reveal differences with controls (Appendix S1, Fig. S2), probably due to the rare COX negative fibers in their muscle biopsy, confirming that myopathy in these patients is frequently very mild or even subclinical. motor spares in isando