Eif4a antibody
WebEGPI-1 is a potent small molecule that inhibits the translation initiation factors eIF4E/eIF4G interaction. EGPI-1 has potent antiproliferative and proapoptotic activity in multiple myeloma cells, Jurkat cells, and A549 lung cancer cell lines, inhibits A549 proliferation with IC50 of 2.61 uM, which is better than that of 4EGI-1 (IC50=58.6 uM ... WebeIF4A, which is a DEAD box RNA helicase (Rogers et al, 2002; Hernandez and Vazquez-Pianzola, 2005). The third component of the eIF4 complex is eIF4G, a peptide that interacts with both eIF4E and eIF4A (Mader et al, 1995; Hentze, 1997; Dever, 1999). In addition, eIF4G interacts with eIF3 (Hinnebusch, 2006) to bridge the mRNA–eIF4
Eif4a antibody
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Web7 sep. 2005 · The function of eIF4G includes circularization of the mRNA by interaction with the cap-binding protein eIF4E and the poly(A)-binding protein (PABP), delivery of the RNA-helicase eIF4A to the 5′ end of the mRNA, and bridging of mRNA and 40S ribosomal subunit by means of eIF3 (1-3). Web2 nov. 2024 · The assembly of cap-binding complex eIF4F, consisting of the eukaryotic translation initiation factor 4E (eIF4E), RNA helicase eIF4A and scaffold eIF4G, is the rate-limiting step in translation initiation, which entails the unwinding of the secondary structure in the mRNA 5’UTR to facilitate recruitment of the 43S pre-initiation complex (PIC) …
Web6 apr. 2024 · plant Anti-EF1A elongation factor 1-alpha / EF-1-alpha ANTIBODY, P13905, eEF-1A. Choose currency: Sign in. ANTIBODY SHOP . Products. Antibodies Plant/Algal . … WebeIF4A (F52) Antibody detects endogenous levels of total eIF4A1, eIF4A2 and eIF4A3 proteins. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification Polyclonal …
WebTo determine the association of eIF4A to preinitiation complex, the fractions of the sucrose gradient were analyzed by immunoblot using an antibody raised against yeast eIF4A. … WebOur eIF4A1 Antibodies can be used in a variety of model species: Canine, Equine, Guinea Pig, Human, Mouse, Porcine, Primate, Rabbit, Rat, Zebrafish. Use the list below to choose the …
WebIn our laboratory, we aim to understand phenomena invisible in experiments by means of quantum chemistry. After completing graduate school, I worked as a researcher at a science and technology think tank for 14 years, and after working at Nihon University School of Dentistry at Matsudo and Hoshi University, I came to the Graduate School of …
WebAnti-eIF4A1 antibody [EPR14506] (ab185946) 研究可靠 —— 各批次间结果一致且可重复 长期批量供应 —— 采用重组技术，可实现快速生产 首次实验即可成功 —— 经过大量验证确认 … ccsax holdingsWebEIF4E Antibodies. (Eukaryotic Translation Initiation Factor 4E (EIF4E)) The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of cellular mRNAs. The encoded protein aids in translation initiation by recruiting ribosomes to ... ccs b 10.2Web29 nov. 2015 · About An accomplished Principal Investigator with expertise in lead discovery and protein design and development. I have over 15 years’ experience of working in research at the interface between academia and industry. I have performed multiple project leadership roles in industrial collaborations involving MNCs and local SMEs and I also … butch eavensonWebBased on 100% sequence identity, this antibody is predicted to react with Rat, Bovine and Pig Target Information eIF4A3 is a member of the DEAD box protein family. DEAD box … butch eastmanWebSanta Cruz Biotechnology, Inc. offers a broad range of eIF4E antibodies. Select eIF4E antibodies from monoclonal antibodies listed below. View detailed eIF4E antibody specifications by linking to the specific product blocks. Select appropriate eIF4E antibodies for your research by isotype, epitope, applications and species reactivity. ccs baby hair - eve 2.0 non hq .packageWebeIF4A. The eukaryotic initiation factor-4A ( eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA … butch eaton saint augustine poolWebAntibody: Affinity purified rabbit anti-eIF4B antibody A301-767A used for WB at 0.04 µg/ml (A) and 1 µg/ml (B) and used for IP at 3 µg/mg lysate. eIF4B was also immunoprecipitated … ccs bacen cnj