Trafficking kinesin protein 1
SpletHow JIP3’s interaction with dynein and kinesin-1 contributes to organelle clearance is unclear. We show that human dynein light intermediate chain (DLIC) binds the N-terminal RH1 domain of JIP3, its paralog JIP4, and the lysosomal adaptor RILP. ... (RAB11FIP3), ninein (NIN), and trafficking kinesin-binding protein 1 (TRAK1). Helix 1 is ... Splet19. jun. 2024 · It is thus unclear how kinesin-1 acts as an efficient transporter in intracellular environments. Here, we demonstrate that TRAK1 (Milton), an adaptor protein …
Trafficking kinesin protein 1
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Splet14. apr. 2024 · Retro-2 is an inhibitor of endosome-to-Golgi retrograde transport of the plant toxin ricin and bacterial Shiga toxin. However, the efficacy of Retro-2 also has been examined against enveloped viruses, such as filoviruses. As a result, Retro-2 is an ebolavirus (EBOV) infection inhibitor. It shows an EC 50 of 12.2 µM in HeLa cells. SpletGene ID: 103137829, updated on 12-Apr-2024. Summary Other designations. trafficking kinesin-binding protein 1, trafficking kinesin protein 1, trafficking kinesin protein 1
Splet07. nov. 2006 · We show that the kinesin-1 cargo protein JNK-interacting protein 1 (JIP1) is localized to only a subset of neurites in cultured neuronal cells. The mechanism of … Splet04. nov. 2024 · TRAK1 trafficking kinesin protein 1 [ Homo sapiens (human) ] Gene ID: 22906, updated on 13-May-2024 Download Datasets Summary Official Symbol TRAK1 …
SpletProtein Trafficking kinesin-binding protein 1 Gene TRAK1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 953 Protein existence … Splet13. okt. 2016 · HAP1 shares a conserved “HAP1_N” domain with TRAfficking Kinesin proteins TRAK1 and TRAK2 (vertebrate), Milton ( Drosophila) and T27A3.1 ( C. elegans ). HAP1, TRAK1 and TRAK2 have a degree of common function, particularly regarding intracellular receptor trafficking.
Spletpred toliko dnevi: 2 · Here, we demonstrate that TRAK1 (Milton), an adaptor protein essential for mitochondrial trafficking, activates kinesin-1 and increases robustness of kinesin-1 stepping on crowded microtubule ...
Splet18. nov. 2024 · The kinesin-3 family motor KLP-4 has also been shown to regulate the anterograde trafficking of GLR-1 in the ventral nerve cord []. Transport of NMDA Receptor by the kinesin-2 motors KIF17 and KIF3. ... Kinesin-1 is not the only motor protein associated with RNP transport. maxwell patrick imagerySplet05. okt. 2024 · Trafficking kinesin-binding protein 1 (TRAK1), TRAK2 and Milton act as motor adaptors by connecting kinesin 1 (KIF5) family motor proteins to mitochondria through mitochondrial Rho GTPase 1 (MIRO1 ... herpes vs yeast infection womenSpletHuntingtin-associated protein 1 (HAP1) was initially identified as a binding partner of huntingtin, mutations in which underlie Huntington's disease. Subcellular localization and protein interaction data indicate that HAP1 may be important in vesicle trafficking, cell signalling and receptor and protein interaction data indicate that HAP1 may be herpes was hilftSpletTrafficking kinesin-binding protein 1 Protein also known as : 106 kDa O-GlcNAc transferase-interacting protein . Gene name : TRAK1; Family name : milton Protein … herpes vs shingles symptomsSplet01. mar. 2009 · TRAK1 (trafficking kinesin protein 1) 2009-03-01 Identity HGNC TRAK1 LOCATION 3p22.1 LOCUSID 22906 ALIAS DEE68, EIEE68, MILT1, OIP106 FUSION GENES Show Gene Fusions Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool Other Information … maxwell park washington dcSpletThe trafficking kinesin protein (TRAK)/Milton family of proteins comprises kinesin adaptors that have been implicated in the neuronal trafficking of mitochondria via their association with the mitochondrial protein Miro and kinesin motors. herpes vs yeast infection symptomsSplet29. mar. 2024 · TRAK1 trafficking kinesin protein 1 Associated conditions. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for... herpes vulvovaginitis treatment